You don’t really make cocaine you extract it. The plant does all the work of making it. The molecule is too difficult to be made economically. This is unlike something like meth where we can synthesis it from scratch.
Those chemicals are used because they are cheap. But there are lots of things you could substitute them with. But it’s important to note that these chemicals are used in the extraction process but there is no significant amount of them remaining in the final product. It’s not like they are mixed in like a cake.
Finally if you worried that gasoline is too toxic then maybe drugs (of any kind) aren’t for you.
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