Why does Propofol put you to sleep so quickly?

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I got a procedure done and they used an anesthesia which I believe is called “Propofol”. It put me out so fast, it felt like I got violently dragged into sleep. Immediately after I saw that white liquid being injected in my vein, I passed out.

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24 Answers

Anonymous 0 Comments

I got propofol when they had to put a camera down my throat God damn that should knock me off so f****** fast I don’t even remember hitting three

Anonymous 0 Comments

I was given something that may have included this when I was getting my wisdom teeth removed (Note: not extracted, as they were cutting them out before they came in). I was a teen at the time.

I counted down from 10, nothing, looked at the anesthesiologist and said “hunh, do you need to give me more of…….” and I was out.

Anonymous 0 Comments

Interestingly the “counting back from 10” comes from the days of using thiopental.
Thiopental works a bit quicker than propofol and will cause unconsciousness after only counting a few numbers.
Propofol doesn’t work as reliably quickly, and generally in elective surgery a lower dose is used so it takes a little longer.
This is why many anaesthetists don’t ask you to count back from 10 anymore. “Think of somewhere nice you’d rather be” is a bit more pleasant.

Anonymous 0 Comments

All the above and also it interferes with memory formation. So you may have been awake for a couple of minutes after you saw it injected, but you have no recollection of this.

Anonymous 0 Comments

It doesn’t put you to sleep right away so much as it hits the “pause” button on your brains ability to record/process sensory information. The result is similar to a blackout episode and eventually the body goes into a more or less suspended animation until it can start processing information again.

However, just like an intense blackout episode, you don’t remember anything that happened between the record button getting paused and when you finally go into that suspended state. So as far as your brain is concerned you were asleep the whole time.

Anonymous 0 Comments

When I was put under formy surgery, I tried to (very poorly) fight the effect so that I could keep telling them about my dog. No counting for me, just pup dates!

Then I refused to ‘wake up’ in the recovery room! They very gently shook me, until I grunted angrily at them 😂

Anonymous 0 Comments

Best nap I’ve ever had in my life. I do remember waking up halfway through (wisdom teeth removal) because mine were very impacted and he was shaking my head back and forth in the most unhinged way trying to dig one of the teeth out. I also clearly remember him raving about how I was the best dental patient he’s ever had, but I’m convinced that wasn’t real 😂

Anonymous 0 Comments

It’s given intravenously (IV). Drugs administered this way enter the bloodstream immediately and can take effect in less than 30 seconds.

By contrast, orally administered drugs typically take about 30-40 minutes. Orally administered drugs are also metabolized by liver “first pass metabolism” which can change or decrease their effects.

Anonymous 0 Comments

I had Propofol with 3 different procedure. I felt so amazing when I woke up. I see why MJ used it every night to sleep.

Anonymous 0 Comments

An anesthesiologist friend told me it is the most abused drug in his field. He heard of anesthesiologist residents using it for a quick nap.