Shouldn’t they happen at around the same age?
In: 9
[Here’s a paper](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543877/) that explains a bit about the mechanisms of puberty. An excerpt:
*Infusion of human kisspeptin-10 (KP10) into the ME of female and male rhesus monkeys at both the prepubertal and pubertal stages stimulates GnRH release in a dose-responsive manner (39,40). Importantly, within the same sex the GnRH neurons in pubertal animals are more sensitive to KP10 than in prepubertal animals, as GnRH response to KP10 at the same dose in pubertal animals is larger than in prepubertal animals. Interestingly, female GnRH neurons are ten-fold more sensitive than male GnRH neurons, as 1) the minimum effective dose is 10-fold less in female than male and 2) KP10 at 0.1 μM induces a larger response in females than in males (33). Pubertal amplification of KP10 action on GnRH release in females is due to the pubertal increase in estradiol, as there is no GnRH response to KP10 in ovariectomized pubertal females (39). Unlike in females, however, the GnRH response to KP10 in males is less dependent on the pubertal increase in androgens, as orchidectomy in pubertal males does not alter the GnRH response to KP10 (33). Therefore, the contribution of kisspeptin signaling to the pubertal increase in GnRH release in both males and females is two folds: 1) a larger amount of endogenous kisspeptin output after puberty onset and 2) an increase in kisspeptin receptor sensitivity of GnRH neurons.*
TL;DR: genders have genetic and morphological differences.
Latest Answers