why does simply having XY or XX chromosomes not necessarily dictate sex?

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i’ve been out of school for a while, but when i was in school, there was no mention of any SRY gene and it’s functions and ability to travel to either X or Y and implications and all of that. It’s a little confusing for me at the moment so could someone explain?

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Anonymous 0 Comments

Because the body is complex.

For instance, there is the androgen insensitivity syndrome which means the body is immune to the effects of testosterone. So you are born as an XY, you have testes that never full form or descend because male hormones have no effect on you and since we all start female in the womb, this genetically created male presents as female.

[https://medlineplus.gov/ency/article/001180.htm#:~:text=Androgen%20insensitivity%20syndrome%20(AIS)%20is,genetic%20makeup%20of%20a%20man](https://medlineplus.gov/ency/article/001180.htm#:~:text=Androgen%20insensitivity%20syndrome%20(AIS)%20is,genetic%20makeup%20of%20a%20man).

And then there are more than just XX and XY combos. You have what’s called fragile X, that’s it, the girl has 1 X. Then you got the ones where you got 3 instead of 2, XXY, XYY and a few others as well.

As you can see, gender and Sex are very complicated, its not just men and women, its a spectrum of presentations where some are more male then others and some are more female that others. Chromosomes play a role as well as your hormones.

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