Why don’t mRNA vaccines overwhelm the body and cause all the cells everywhere to create proteins?

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I don’t even know how stupid this question is. I was just watching [a video](https://www.sartorius.com/en/applications/biopharmaceutical-manufacturing/vaccines/vaccine-development/mrna-vaccines) on how mRNA vaccines are designed to work and I fully admit my biology is disgustingly rusty.

My main question is if we are injecting the blueprints instead of the protein itself, how are we preventing the body from taking that blueprint *everywhere* and having it be overwhelmed by the vaccine production–preventing it from producing other key and important proteins/stuffs in the body? Aren’t there areas of the body we don’t want producing this protein (like the heart or brain maybe)? How do we avoid the blueprint from getting there?

I feel like the answer is obvious, but I don’t know what to research. I’d love to understand this better.

In: Biology

3 Answers

Anonymous 0 Comments

I know what you mean because I’ve thought about it too. At any given moment there are millions of distinct mRNA strands in your body to produce millions of different proteins and enzymes. Adding just one more won’t really make much of an impact. They also don’t inject very much into you. I could see that if you injected gallons concentrated mRNA it might reduce the ability of your body to produce the proteins it needs, but this is 0.3 mL or 0.06 tablespoons.

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