We already have a few examples, apache spark (basis of data bricks) does this.
A database, at its simplest, is made up of tables with rows and columns. You can store these as files, a good way to do this is having each column as a file (this is how apache spark works, with parquet being the file format, and those files being stored on a file system (aws s3).
It works incredibly well at some things, less well at others.
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