Skipping whatever opinion you may have on Michael Jackson his case is a great example for it. In his final days of life he suffered from severe insomnia so he paid off a doctor who was putting him to sleep by using propofol – anesthetic drug and it didn’t work very well. He was still exhausted, tired and depressed so during the day he was using other drugs to stimulate himself and appear to be in great shape.
At the time he was working on a big event that supposed to pay off his massive debts, but inability to sleep and forcing himself to function while using crazy mix of drugs eventually led to his tragic death. It’s not eli5, but it’s a great example of someone trying this method with fatal failure.
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