For untold billions of years life used to be single cell. Big multicellular organisms, like us, only evolved recently. When that happened the new organisms kept the vast majority of their predecessors DNA code, which have been optimized for a long time for single existance. Our cells have a thin layer of control and coordination on top of a huge legacy code base built for single cell existance. When that thin layer breaks down in one or a few of our dozens of thrillions of cells, and it/they revert back to the rules of single cell existance and multiplication we get the start of a cancer.
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