While I can grasp the idea that low blood sugar means “low immediate energy supply”, how come that too much sugar in the blood can cause harm?
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Glucose when present in high concentrations can react with cell signalling molecules on the surface of cells. This prevents the cell from receiving the correct signals and becomes desynchronised from the rest of the body. It can also cause membrane stiffening preventing substances from passing into the cell or the cell moving to let other cells past.
These are called rAGES (reactive advanced glycosylation end-products), these are also produced when you fry meat. So in effect having high blood sugar slowly fries the inside of the veins arteries and capilaries, leading to nutrients and immune cells being trapped inside their bloodstream and toxins being trapped outside.
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