If you’re cycling through the water every day, then not a big deal. But you don’t want it to sit stagnant for any length of time.
I just got back from 2 weeks vacation and left my water bottle about half full on my desk. When I opened it made the “pssht” sound of releasing gas and smelled like death. It’s currently getting sterilized with bleach. And that was just filtered tap water in it, nothing else.
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