When you eat regularly, your stomach is always ready for food – and when it doesn’t get it, your stomach starts to rumble and growl, basically telling you “I’m hungry, feed me”. When that goes on for a while, it starts to feel uncomfortable as the acids in your stomach start to break down the protective stomach lining (it’s basically a layer of phlegmy stuff that stops the acid from burning a hole through your stomach)
When you go for a long time without food, your body recognises this. So it says to your stomach “You’re not getting any food, so take a rest” and then you start to use up all energy stores your body has, so sugars and fats, and as long as you have water, your body can survive on those fats for a couple of weeks, I think.
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