We aren’t really designed to handle those kinds of things.
Things like heroin, crack, or whatever, just aren’t seen in nature, we never evolved to handle them. They essentially short circuit natural processes in our bodies. Other things like fat, salt, sugar, we evolved to crave because we definitely need them, but they were never plentiful. So we evolved to seek out the limited amounts around for our survival
It’s maybe kind of like saying if trees evolved to survive better when its warmer, why do they catch fire when it gets really hot?
Trees evolved to enjoy the right temperature on the planet they evolved on. Humans evolved to handle the environment they evolved in and do best there. Introducing harmful things like heroin, meth, huge amounts of booze, etc, is creating novel conditions that we were simply not built to handle well, because those conditions never existed until recently.
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