Why is the condition tardive dyskinesia caused by antipsychotics often permenant?

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According to most research studies Tardive Dyskinesia is often permanent.

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Tardive Dyskinesia only develops if you’ve been on antipsychotics for months or years. We don’t fully know the biochemical mechanism behind the condition, but long term use of antipsychotics causes long lasting or permanent changes in brain chemistry.

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