Why we use not opioid antagonists to treat addictions to opioids faster?
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Addiction is not the same as having opioids in your body. OA basically rapidly converts the opioids in your system into something that doesn’t trigger your receptors. Now let’s think of this another way. Do you know what it feels like to be thirty? How about the relief you feel when you get a drink? Now imagine, no matter how much you drink, the feeling of dry mouth and sticky tongue and chapped lips doesn’t go away. The feeling instead gets worse and worse because you can’t sate the need. So even tho you’re getting what you need, your warning system (aka symptoms) doesn’t go away. In this case (which is also how addiction works) no matter how much water you drink the symptoms of thirst continue. So addiction is basically the symptom of desire going on and on and on…. How do you cure your brain from desire? By eliminating the water? By taking so much water your bladder will burst like a water balloon? Neither. By reprogramming your brain. You can reduce the symptoms by still giving the drugs and by slowly lowering the dose, the brain will learn how to function without the desire plaguing you every moment. Eventually you can remove the effects of the drugs (tho sometimes the desire is not addressed which inevitably leads to relapse) but the desire and the effects of the drug are not the same. It’s two separate things that must be addressed together for the greatest chance of success
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