Because it’s fun. Butt seriously (pun intended), some people have explained things below like it bypasses nausea and the need to swallow, which can be important in many instances. However, another important factor is that many medications, whether by intentional design or by the nature of the medicines chemical structure, aren’t absorbed well after passing through the stomach acids or through muscle. This means they need to be absorbed directly through intestinal lining. The only way to do that while bypassing the stomach is to go the other way.
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