Why would you want to use a suppository over a pill, shot, lotion, etc?

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Why would you want to use a suppository over a pill, shot, lotion, etc?

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Suppositories can often be used without the same side effects as oral medication. For example, oral progesterone (a hormone) causes nausea, but taken as a suppository it has the same medicinal effect without the nausea. Similarly a THC suppository can give pain relief without causing a high like oral use would

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