1. The patient might be a young child (or a challenged adult) whom you cannot convince to take a pill.
2. The patient might have nausea and unable to hold anything in, so they’d just vomit right out any pill they take.
3. You generally need at least some minimal training or prior experience to do shots correctly. There is also pain and some risks.
4. Suppositories are more effective because they get absorbed into the bloodstream right away and don’t go through the patient’s stomach and liver first.
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