Why is the shingles vaccine only recommended for use on patients 50 years or older?

695 views
0

Why is the shingles vaccine only recommended for use on patients 50 years or older?

In: Biology

Because 50 is when your odds of getting shingles starts to increase.
This is important because if you develop a drug you need to run studies to show it’s effectiveness. Since you want to make things easy when you’re running your first study you concentrate on groups that are most susceptible to the condition you’re trying to fight (because then you can keep your studies small and still get a meaningful amount of ‘signal’ in your data). In the case of the new “Shingrix” shingles vaccine GlaxoSmithKline ran
studies like [this one targeting the 70+ age group](https://clinicaltrials.gov/ct2/show/NCT01165229?term=NCT01165177&rank=3), and [this one targeting the 50+ age group](https://clinicaltrials.gov/ct2/show/NCT01165177?term=NCT01165177&rank=2). This means that the effectiveness of this vaccine has only been proven in the 50+ age group, so that’s all that groups like the CDC will recommend.