Yes. An example is sports – very few catchers and quarterbacks are taught to throw left handed (baseball because of right-handed hitters blocking the throw from the plate, football because it messes up with how playmaking works), so even naturally left-handed people will learn to play the game that way. There is nothing preventing a naturally left-handed athlete from playing at the top levels of either of those positions, but they will generally all be playing as though they were right-handed.
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