I guess they take a longer path to ensure that the things are controlled and replication is accurate. But is it possible to implement these checks and processes directly in DNA to proteins?
In: Biology
The functional hurdles are that Ribosomes read the genetic material mRNA and generate the protein and this has been well described here, so I won’t further that completed answer.
The PRACTICAL HURDLE is that protein can be generated but must be TRANSPORTED to go where it needs to once manufactured and the DNA is housed in the Nucleus which has no such mechanism, while the Endoplasmic Reticulum is where most of the ribosomes reside. The nucleus is incredibly efficient for space and crams all of the DNA into it with zero room for extra stuff. If you were transcribing the DNA into protein directly, it would create tremendous “muck” around the DNA and gum up the whole system (remember protein is often very sticky). Instead, itty bitty threads (mRNA) are transcribed which can be easily moved out of the nucleus and proteins are synthesized off-site which can then be efficiently transported/modified/etc as needed for their ultimate purposes via the ER and the Golgi Apparatus. Imagine three buildings next to each other: one building holds all the plans, the next one holds all the manufacturing, and the last one has shipping.
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