Thinking of it in terms of “combat” or “fighting” might be a little misleading, but yes, white blood cells can “lose.” HIV in particular is a virus that defeats white blood cells. The white blood cells, specifically a type of white blood cell called a CD4+ cell, tries to bind to the HIV particle to deactivate it, but the HIV actually enters the CD4+ cell and hijacks it to produce more copies of the virus, breaking the cell apart and killing it in the process.
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