Yes. And vice versa—I use anti inflammatories like NSAIDs for severe allergies.
But basically, there are slightly specialized antihistamines that work better on skin, lungs, mucus membranes, etc. But on the flip side, once the _initial_ anaphylactic reaction is over, they fill you with generalized antihistamines to reduce the reaction.
Source: take 7 daily allergy medicines, not all of which are antihistamines
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