No, but it depends on the type of fever reducer. If you talk about aspirin,it stops the synthesis of some substances that our body was producing to fight off an infection(called prostaglandin),with unwanted effect on hypothalamus. Hypothalamus has an innate “set point” of what an ideal temperature of our body should be. Prostaglandins increase this set point so our body raises its chemical activity to pump up heat production. Aspirin blocks synthesis of prostaglandins,so no increase in set point. You don’t need prostaglandins normally to maintain your set point though, so unless you really really overdose, it won’t be a problem. And even if you do overdose,a fever would be the least of your worries.
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