When there is excess glucose in the blood, insulin promotes glucose uptake mainly by the liver, adipose, and skeletal tissues. When there is low glucose in the blood, glucagon promotes release of glucose into the bloodstream, which will then be used by the cells for energy (e.g. skeletal tissue). So, in this case, both insulin and glucagon will both lead to glucose uptake in the skeletal cell? Or does insulin promote storage of glucose within the skeletal cell, which then gets released into the bloodstream by glucagon, but re-enters the skeletal cell for energy consumption?? Tried searching online for references, but couldn’t find the answer. Your insights will be much appreciated!
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What you need to know is that there are two types of cells in the body that can survive exclusively on glucose and they are the red blood cells and neurones so if your blood sugar is low those two suffer.
The brain with low sugar leads to agitation but with very low sugar for a prolonged time leads to coma then death.
On a regular basis insulin stores glucose in several tissues so that when you need it glucagon can take it out to keep regular and healthy levels of glucose in blood to keep the brain working.
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