How does an adverse reaction occur after taking medication?
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Some adverse effects are the nature of the medication. Aspirin, or even more “blood thinners” like warfarin (Coumadin) apixaban (Eliquis), and others can cause bleeding because of how they work. Blood pressure medications can cause too low blood pressure with lightheadedness if the dose is too high. Other times it’s less directly linked to the intended purpose but makes sense because of what the medication does. Antidepressants like sertraline (Zoloft) can cause diarrhea because gut is also full of serotonin receptors even though they have nothing to do with brain. All those are adverse but not really unpredictable.
Other adverse effects are like a severe allergic reaction to penicillin. It has nothing to do with how the medication works, it just happens. Other medications seem to have consistent but not well explained adverse effects, so they probably interact with some cells or proteins in ways that aren’t understood.
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