Eli5: does mixing alcohols really make you sick? If it does, why?

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I’ve always heard things like liquor before beer. You’re in the clear and that mixing brown and white can go bad, but why are you not supposed to mix alcohols?

In: Biology

48 Answers

Anonymous 0 Comments

There is a good article on this at healthline

https://www.healthline.com/health/alcoholism/congeners

Basically, there are things other than ethanol in your drinks.

In the discussion of “what is in your drink?”, they call these things “**congeners**”.

>Examples of congeners the distillation process makes include:

* acids
* alcohols, such as isobutylene alcohol, which smells sweet
* aldehydes, such as acetaldehyde, which often has a fruity smell present in bourbons and rums
* esters
* ketones

>The amount of congeners present in alcohol can vary. As a general rule, the more distilled a spirit is, the lower the congeners.

>**This is why some people may find that “top shelf” liquors that are highly distilled don’t give them a hangover as much as a lower-priced alternative.**

This is an important bit.

>**drinking alcoholic beverages that have more congeners usually causes a worse hangover than drinks with fewer congeners.**

In university, we “liberated” a 50 gallon drum of medical grade (95%) ethanol.

Never a hangover in spite of some excessive drinking.

This was interesting

>Researchers currently believe a hangover is the result of many contributing factors, including:

* how much a person drank
* sleep duration
* sleep quality

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