Currently working on an oncology presentation. Our professor assigned us a chemotherapy and we have to do in-depth research on it (indications, mechanism of action, etc). The drug I was assigned specifically is used for FGFR2 fusions. I’ve scoured through Pubmed, BioMed, and various oncology journals and I cannot get a straight answer as to what an FGFR fusion even is. All I’m getting is that it can amplify FGFR signaling, leading to proliferation, which I understand. I just don’t want to get to my presentation and my professor ask what an FGFR fusion is and I have no idea how to respond
Hopefully someone here is knowledgeable on this! Thanks!