ELI5. Grapefruit juice and the effects on mental health medication?

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To me it’s interesting that grapefruit juice is listed as a “no no” while taking antidepressants/anti-anxiety medication.

I’ve looked into it and I still don’t understand. Can someone explain why you aren’t supposed to mix them? I’m only asking because I like a good Ruby Grapefruit White Claw once and a while…

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13 Answers

Anonymous 0 Comments

It’s not just mental health medication. It’s tons of medications and not because the juice interacts directly with the drug, it inactivates enzymes that metabolize many things which can alter the duration or the dosage you are taking.

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