I always hear people say the monoamine hypothesis of depression is outdated, so what’s actually happening and why is their a delay in symptom reduction when starting? Brain changes are seen a few hours after first dose
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A very basic explanation is that they connect with seratonin (a hormone which helps regulate mood and mental function) receptors to encourage your body to produce more seratonin and level out your hormones. However, there are dozens of different kinds of anti-depressents. Patients may trial any number of medications till they find one that works, i went through 3 personally. Each person reacts very differently.
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