Eli5 How do birth control pills not cause a build up in uterus lining

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In a normal period, the uterus lining is thickened and then shed during the period.

What happens to the lining when using birth control pills? If it’s not shed does it not just keep on getting thicker and thicker?

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Anonymous 0 Comments

They do if you use them wrong. The estradiol builds up the uterine lining, and the progesterone analog keeps it from shedding. If you use progesterone-only pills, no problem. If you use the 28-day cycle packs that give you a period every month, no problem. If you use the packs that give you a period once every three months, no problem. If you use Nexplanon, hormonal IUD, or depo shots, those are progesterone only so no problem.

If you use a combination of estradiol and progesterone analog with a sufficiently high dose of estradiol, and you never take a break for a period, then the uterus lining does start to build up and cause problems. If you take estrogen-only pills, which no doctor will ever prescribe you for birth control, that also will cause problems. Such as break-through bleeding and increased endometrial cancer risk. And when the period finally does happen, it is a thoroughly unpleasant experience.

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