Eli5: how do drug trials work for risky medicine so that it doesn’t kill those participating?
In: Biology
I am no expert on this but my stepdad has run a lot of clinical trials and told me about them. The level of risk they’re willing to take with a drug also depends on the mortality of the thing they’re trying to treat. So if you’re trying to treat a really deadly cancer with few other known treatment options, they’ll tolerate a more risky drug trial, but if it’s a vaccine that you’re giving to large numbers of otherwise healthy people, it has to be really really *really* safe.
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