eli5 How do scientists make microscopic machines and nano bots?

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For example I just saw an image from an electron microscope that showed a nano injector used to inject dna into a single cell.

And the machine looked highly engineered and obviously man-made with crisp and elegant structures. But it is small as heck. It’s insane

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Link for photo I am referencing: https://www.reddit.com/r/interestingasfuck/comments/1367dzm/a_scanning_electron_microscope_image_of_a

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