It can rupture blood vessels and cause haemmorhaging.
It can disrupt the function of the organs/structures it invades (eg. having a big lump in your lung makes breathing problematic…)
But one of the biggest effects is that it just floods you with cellular waste-products. You can end up with *pounds* of cancer in you, and the thing about cancer is that its metabolism is turned up to 11 all day errday, so all that tissue is *constantly* pissing in your bloodstream and just plain poisoning you faster than your liver and kidneys can keep up with.
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