Eli5: How does the brain detect the severity of pain?

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Eli5: How does the brain detect the severity of pain?

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The brain detects pain by reading chemical signals sent from parts of the body. The greater the pain experienced, the greater the amount of chemicals being sent to the brain.

Pain medications work by blocking the receptors in the brain that react to these chemicals. The pain is still there and the body is still sending signals, but the brain is unable to react to them.