It’s quite dilute but aids in digestion of food and control of harmful bacteria.
Parietal cells (Proton pumps) activate pepsin. Pepsin is used to digest proteins and if you have heartburn, regular oesophageal exposure to pepsin can cause Barrett’s oesophagus (esophagus -US). This change in the cells can lead to oesophageal cancer. Cell membranes have cell proteins and so pepsin can damage them.
Proton pump inhibitors (H2 receptor antagonists) are sometimes used to reduce the activation of pepsin. A better way to protect would be to use an ARFOS (alginate rafting forming oral suspension) that can coat and protect. Gaviscon is a popular choice in the U.K. to prevent or reduce heartburn. Others are available.
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