The Sentinelese are part of a larger group of people living on islands in that whole region. They used to trade with other islands but the modern age appears to have cut them off from the larger community. So even though they were just a small group, they were part of a much larger population who they traded and had children with. Will being a small group isolated on an island be bad for their genetics over the course of a few more generations? Possibly. But we have no way to assess that since we are no-contact with them.
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