eli5 what are lethal alleles

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how do they come about, how can they kill organisms

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Five year old version; Imagine you’re trying to drink a Slurpee using two straws, one your mom gave you and one your dad gave you. Oh no! One of your straws has a hole in it! That’s ok, you still have another. Now imagine both your straws have a hole in them. You can’t drink the Slurpee of life now!

If you have one damaged straw and one normal one, you’re ok. When your kids asks for a Slurpee with two straws though, you have a 50/50 chance of giving them the broken one. If your partner also has a broken straw, your kid has a chance of not getting to drink any Slurpee if you both give them broken ones. But as long as everyone has at least one good straw they’re ok.

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