Eli5: What causes the rash during Shingles?

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How does nerve damage cause rash on the skin? And what exactly hurts, the nerve damage or the blistery skin?

Also how do antidepressants relive the pain?

In: Biology

3 Answers

Anonymous 0 Comments

My brother has shingles twice. He said the pain is mostly in the nerves while the blisters (when open and weeping) sting and hurt like sunburn. In all honesty never heard of antidepressants helping with the pain, my brother was on a strong course of antibiotics, pain relief and lotion for the blisters. He was ill for about 2 months, 3 weeks being the painful shooting pains in his chest.

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