Tetany, aka spasm. The muscle/neuromuscular junction is unable to properly repolarize (reset) after firing (depolarizing), often due to electrolyte or pH imbalances in and around the muscle cells. All the muscle and nerve cells in the body use the potential energy from concentration gradients of ions, particularly calcium, to drive the firing of electrical impulses from one end of the cell to the other. When this balance is thrown off, the signal is “stuck” waiting for that gradient to build up to a sufficient level of energy to fire again.
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