For me it’s when the ‘fight or flight’ response keeps getting activated, so my heart rate goes up & I get hyper-aware of my surroundings. I’m sure this is a great response for dealing with being chased by a sabre-toothed tiger, but in the modern world it’s completely inappropriate for dealing with the actual problem, which maybe something at work that requires clear-thinking, or maybe just the need to go to sleep at night, so it’s bloody exhausting… which makes it hard to have a clear head the next day, and round and round we go…
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