Eli5: what is the difference between a generic drug to the original drug, and why do some doctors will swear by the original drug?

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Eli5: what is the difference between a generic drug to the original drug, and why do some doctors will swear by the original drug?

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Anonymous 0 Comments

another interesting difference between brand name and generics that i haven’t seen mentioned is that generics are allowed to differ in chemical matter if they show a certain (high) degree of efficacy equivalence. that means that for some (small number of) people the generic may be less effective than the original brand name. i speak from personal experience with a medication i take being expensive and insurance wanted me on the generic. problems arose quickly and it took nearly a year to figure out that my body was absorbing only ~50% of the active ingredient due to the generic being slightly different. I eventually got permission to switch back to brand name & problems went away immediately

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