Eli5: what is the difference between a generic drug to the original drug, and why do some doctors will swear by the original drug?

Question

Eli5: what is the difference between a generic drug to the original drug, and why do some doctors will swear by the original drug?

In: 1046

Answer 1

Bioequivalent drugs (aka generics) go through a rigorous testing to ensure efficacy prior to entering the market.

It depends on what the drug treats, but there are variances allowed for the active ingredients and non-active ingredients may be different than a branded drug.

If a name brand drug works for you and your insurance requires the generic but you experience side effects or the medication doesn’t work the same, you should be able to go back to your Dr. to document the changes you experience with the generic and the Dr. may be able to get your branded drug covered or switched to another named brand drug (usually within the class instead.)

It’s the lack in variance in the branded drug that your Dr. Has come to depend on to treat the disease/ condition.