eli5: Why and how bad is vaping without nicotine/THC?

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eli5: Why and how bad is vaping without nicotine/THC?

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My understanding is the heating the propylene glycol and glycerol in e-liquids creates compounds that release toxic chemicals that are harmful to you with and without the additions of nicotine or THC [source](https://www.nejm.org/doi/full/10.1056/NEJMc1413069). So in short still bad. Short term can cause inflammation, lung and throat irritation, I’m sure there’s more data on long term but cbf finding it.

THC additions have been shown to create a “sticky substance” in your lungs which can lead to further lung injury [source](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952050/). EDIT: THC when paired with vitamin E acetate as thickening solution not THC on its own

Nicotine additions bring in all the side effects of having nicotine in your system. Including an increase in blood pressure, heart rate, flow of blood to the heart and a narrowing of the arteries. Plus a general risk of addiction leading to more vaping and the higher chance of starting smoking.

ELI5 smoking the vapour is as bad and will result in damage to the lungs and throat, but no side effects or issues that come with the addition of nicotine or THC.

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