eli5: Why are fevers one the first symptoms to go away?

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If a fever is there to raise a body’s temperature to help kill off a virus – why at the later stages of infection does the fever stop being a symptom even though other symptoms are still present? If other symptoms are still present then the host must still carry the pathogen, so surely the fever should last until the host is healthy?

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Anonymous 0 Comments

For the same reason that you often find people do froze to death naked or semi naked. After a while, your automatic systems that try to keep you alive ‘get tired’ and give up. In your body, your hypothalamus controls temperature. It sends out signals that tell the muscles to generate heat. They do this first through enhanced metabolism, and later by physical movement (shivering). But this system depends on the muscles being able to maintain, which they can’t forever. Sooner or later, they give up, they’re just too tired to continue heat generation, OR the brain has decided that the remaining energy it has is better spent on keeping the brain and other systems operational as opposed to maintaining heat.

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