eli5: why are the long term effects of herbal medicines unknown?

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for example, ashwagandha or valerian. whenever you search them up it states something akin to “safe to use for up to 6 weeks. long term effects are unknown”

people have been using these medicines for centuries… can’t they just conduct research?

In: Biology

7 Answers

Anonymous 0 Comments

one thing to consider here maybe:

while there is no /not enough studies on long-term-effects on certain herbs, there might very well be studies on substances these herbes contain!

herbal medicine has the disadvantage that you’ll always consume a cocktail of different substances, while modern medicine focusses on extracting (or recreating) the substance that they want to use.

[https://en.wikipedia.org/wiki/Metformin](https://en.wikipedia.org/wiki/Metformin)

This medication is for treatment of diabetes. It’s origin is a natural herb called goat’s rue (Galega officinalis). It was used as a healing herb long before modern medicine.

The consumption of this herb, however, had plenty of negative side-effects- which is why they identified the substance that is helpful and recreated it chemically – this medication, called Metformin, is working much better with less side-effects.

To make **a human study on long-term effects of goat’s rue would therefore be unethical**

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