Eli5: Why can’t regular blood transfusions be used to treat AIDS patients? Wouldn’t this dilute the amount of HIV and maintain CD4 cell count?

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*prior to antiretroviral drugs

In: Biology

4 Answers

Anonymous 0 Comments

Because the virus isn’t just in the bloodstream. Just because it can be transmitted that way doesn’t mean that’s the only place it exists. The virus infects CD4+ cells, some of which are in the bloodstream, but more of which are in the lymphatic system, the gut, and a bunch of other tissues. A blood transfusion would only remove the viral particles in the blood, and the rest will remain where they are and continue to infect new CD4+ cells, so the person’s overall viral load would just go right back to where it was.

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