Eli5: Why can’t regular blood transfusions be used to treat AIDS patients? Wouldn’t this dilute the amount of HIV and maintain CD4 cell count?

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*prior to antiretroviral drugs

In: Biology

4 Answers

Anonymous 0 Comments

It infects T cells in your body, they exist in lymph nodes the gastrointestinal tract etc, so even IF you were able to remove all the infected blood and replace it, you still would have HIV in the T cells in the tissues, which would simply infect the blood again.

HIV isn’t just a blood disease, it’s just also found in the blood. It’s totally body invading and you really can’t do much about that. There’s too many organs and tissues that will retain the virus and as your blood travels through those tissues as it does, it’ll pick it back up and back to square one.

It’s like under 5% of the cd4 t cells that actually reside in the blood… The rest is in our organs, tissue, basically everywhere.

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