It is widely known that upon contact with new civilization, the indigionous people can be wiped out because they are not immune to our sicknesses; wouldn’t they also have some illness that europeans aren’t immune to?
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Native Americans had few dangerous infectious disease, only syphilis. Other indigenous people they met afterward like Pacific Islanders didn’t have any. That’s because those population had a low population density and very little animal husbandry, so they weren’t at high risk of developing epidemics.
Europeans did die a lot from the plague and smallpox which came both from East Asia. It just happened before the colonization of the Americas.
Europeans also died a lot from tropical disease, often mosquito-born, in Africa, the Americas, and Asia, but those diseases stayed in those regions. They couldn’t spread in temperate regions, including Europe.
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