It is widely known that upon contact with new civilization, the indigionous people can be wiped out because they are not immune to our sicknesses; wouldn’t they also have some illness that europeans aren’t immune to?
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The short version is: because Europeans lived like dirty pigs, while the pigs (or all animals) lived even worse. Europe had dense populated but very unhygienic cities for many cneturies, perfect breeding grounds for all kinds of things. The animal farming that was much less in the rest of the world, or less close and dense, increased the chance for illnesses to jump host species.
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