eli5: Why do people who have major blood loss need transfusions?

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If a person gets an injury and has major blood loss they get a transfusion. How come their blood doesnt just replenish? If someone donates blood how come they dont need a transfusion after? In both scenarios people are losing blood but why cant someone who lost blood from an injury just naturally make more blood to fix that?

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Anonymous 0 Comments

The amount of blood given in donation is well within the limits that the body can survive for a time without, and readily rebuild and come back from.

With traumatic injury, when massive amounts of blood are lost at once, there is not enough left to keep oxygen and nutrients flowing to the heart and other organs. The transfused blood brings the body back up to a functional level of blood, and then the body *can* take over and make more.

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